Estrogen biosynthesis pathway . Note: DHEA, dehydroepiandrosterone; OH, hydroxy. Credit:Research from the University of Cincinnati shows that exposure to PFAS may delay the onset of puberty in girls. The research was published in the journalThis study is the first longitudinal research that included the component of the role hormones play in the delay, according to Susan Pinney, Ph.D.
"Puberty is a window of susceptibility," Pinney says."Environmental exposures during puberty, not just to PFAS, but anything, have more of a potential for a long-term health effect. What these have done is extended the window of susceptibility, and it makes them more vulnerable for a longer period of time."
The results found that 85% of the girls in the two cohorts had measurable levels of PFAS. Pinney says this PFAS research is unique because the hormone component was included and they discovered evidence of decreased hormones.
Pinney points to several factors playing a role in PFAS exposure in Greater Cincinnati. The Ohio River is the main source of drinking water in the area and a DuPont plant near Parkersburg, West Virginia, released PFAS into the river for decades which flowed downstream to major water intakes on both sides of the river near eastern Hamilton County. PFAS were also present in firefighting foam and there is a firefighting training ground near those same water intakes.
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