is accumulated over the course of the day didn't matter as much as the total time spent sedentary each day. Whether spent in extended periods spanning several hours or spread out intermittently throughout the day, total sedentary behavior had a similar association with dementia according to study author David Raichlen.
"Many of us are familiar with the common advice to break up long periods of sitting by getting up every 30 minutes or so to stand or walk around. We wanted to see if those types of patterns are associated with dementia risk.
Researchers used data from the U.K. Biobank, a large-scale biomedical database of participants across the United Kingdom, to investigate possible links between sedentary behavior and dementia risk. As part of a U.K. Biobank sub-study, over 100,000 adults agreed to wear accelerometers, wrist-worn devices for measuring movement, for 24 hours per day for one week. The researchers focused on a sample of approximately 50,000 adults from this sub-study over the age of 60 who did not have a diagnosis of dementia at the start of the study.to analyze the large dataset of accelerometer readings and classify behaviors based on different intensities of physical activity.
After an average of six years of follow-up, the researchers used inpatient hospital records and death registry data to determine dementia diagnosis. They found 414 cases positive for dementia.
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