Sitting directly on a transplanted kidney, the ultrathin, soft implant can detect temperature irregularities associated with inflammation and other body responses that arise with transplant rejection. Then, it alerts the patient or physician by wirelessly streaming data to a nearby smartphone or tablet.
Northwestern's John A. Rogers, a bioelectronics pioneer who led the device development, said it's critical to identify rejection events as soon as they occur. Gallon also is a professor of nephrology and hypertension and organ transplantation at Northwestern University Feinberg School of Medicine. Rogers is the Louis Simpson and Kimberly Querrey Professor of Materials Science and Engineering, Biomedical Engineering and Neurological Surgery at Northwestern's McCormick School of Engineering and director of the Querrey Simpson Institute for Bioelectronics . Gallon and Rogers co-led the study with Dr.
Miniature electronics accompany the sensor. The electronics include a tiny coin cell battery and Bluetooth communications. Credit: Northwestern University Not only does the new device detect rejection signs earlier than other methods, it also offers continuous, real-time monitoring. Right after transplant surgeries, patients might get blood tests more than once per week. But, over time, blood tests become less frequent, leaving patients in the dark for weeks at a time.Dr. Joaquin Brieva, a Northwestern Medicine dermatologist, is familiar with waiting and wondering.
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