Obese microbiota is causal to instigate elevated gut permeability, inflammation and metabolic dysregulation. Mice receiving FMT from both db/db and DIO mice showed significant increase in FITC 4kDa-dextran , endotoxin leakage from gut to blood compared with their lean control FMT recipient mice.
Intestinal permeability, also known as leaky gut syndrome, is a theoretical condition where the intestines leak water and nutrients. That can lead to inflammation and changes in the normal gut bacterial which in turn could cause problems within the digestive tract.
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