Positive metabolic effects of gastric bypass found to disappear quickly

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A new study from Lund University in Sweden raises questions about the efficacy of bariatric operations involving gastric bypass. The results show that the biggest metabolic changes happened directly after surgery. Just a year after the operation, the concentration of metabolites and fats had returned to almost the same levels as before the procedure.

, the researchers studied the metabolism of overweight individuals before and after they had a gastric bypass operation. The study shows that the biggest changes happened straight after the procedure.

"Just following up on the weight of people can be a blunt instrument for studying the effects of the procedure. Our study provides a greater understanding of what happens to the metabolism in connection with a gastric bypass operation," says Peter Spégel, associate professor of molecular metabolism at Lund University, who led the study.The study was based on data from 148 people with and without type 2 diabetes who underwent a gastric bypass operation in Sweden.

 

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