High caffeine consumption linked to changes in dopamine function in Parkinson's patients

May 28 2024Turun yliopisto Regular high caffeine consumption affects dopamine function in patients with Parkinson's disease, shows a new international study led by the University of Turku and Turku University Hospital in Finland. Caffeine consumption before undergoing diagnostic brain dopamine imaging may also affect the imaging results.

A follow-up study led by the University of Turku and Turku University Hospital in Finland examined how caffeine consumption affects brain dopamine function over an extended period in patients diagnosed with Parkinson's disease. The dopamine function of the brain was assessed with single photon emission computed tomography to measure dopamine transporter binding.

Valtteri Kaasinen, Professor of Neurology at the University of Turku and principal investigator of the study The findings revealed that patients with a high caffeine consumption exhibited a 8.3-15.4% greater decrease in dopamine transporter binding compared to those with a low caffeine consumption. However, the observed decline in dopamine function is unlikely to be due to a greater reduction in dopamine neurons following caffeine consumption.

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