May 14 2024NYU Langone Health / NYU Grossman School of Medicine Artificial intelligence computer programs that process MRI results show differences in how the brains of men and women are organized at a cellular level, a new study shows. These variations were spotted in white matter, tissue primarily located in the human brain's innermost layer, which fosters communication between regions.
Our findings provide a clearer picture of how a living, human brain is structured, which may in turn offer new insight into how many psychiatric and neurological disorders develop and why they can present differently in men and women." Lui, a professor and vice chair for research in the Department of Radiology at NYU Grossman School of Medicine, notes that previous studies of brain microstructure have largely relied on animal models and human tissue samples.
According to the results, all of the models correctly identified the sex of subject scans between 92% and 98% of the time. Several features in particular helped the machines make their determinations, including how easily and in what direction water could move through brain tissue. Bayanagari cautions that while the AI tools could report differences in brain-cell organization, they could not reveal which sex was more likely to have which features. She adds that the study classified sex based on genetic information and only included MRIs from cis-gendered men and women.
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