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Plant virus-derived treatment shows promise against metastatic cancers

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Breast Cancer,Cancer,Colon

An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study from the University of California San Diego.

May 13 2024University of California - San Diego

Here, we do not treat established tumors or metastatic disease-;we prevent them from forming. We are providing a systemic treatment to wake up the body's immune system to eliminate the disease before metastases even form and settle." The researchers tested the efficacy of the treatment in mouse models of colon, ovarian, melanoma and breast cancers. Mice injected with cowpea mosaic virus nanoparticles-;and then challenged with metastatic tumors a week later-;exhibited improved survival rates and reduced tumor growth compared to untreated mice. Even when challenged with new tumors a month later, treated mice exhibited similar outcomes.

 

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