Gene linked to intellectual disability can regulate learning and memory

May 8 2024University of Exeter

Now, researchers at King's College London, the University of Exeter and the University of California Irvine have found that reduced function of the gene in the brain results in loss of learning ability and memory and a reduction in the brain's ability to strengthen connections between neurons, which is key in the formation of memories.

Professor Albert Basson, whose research group began the work at King's College London and has since moved to the University of Exeter, said: "Memory and the ability to learn are fundamental to our intellectual potential, yet we still have a lot to learn about the underpinning mechanisms.

Related StoriesDr Leticia Peres-Sisquez who performed the research at King's College London, said: "We set out to investigate whether KDM5B's ability to modify genetic material has a direct impact on learning and memory. We've discovered that the gene has a direct impact on learning and memory – which is distinct from any effect during brain development.

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