Researchers transformed skin cells into eggs that could be used to create healthy embryos.Sperm-injecting robot achieves a baby-making breakthrough, 2 girls bornIVG was accomplished by transplanting the nucleus of a skin cell into a donor egg that lacked its own nucleus.
“The goal is to produce eggs for patients who don’t have their own eggs,” said Shoukhrat Mitalipov, senior author and director of the OHSU Center for Embryonic Cell and Gene Therapy in the press release. The researchers relied on somatic cell nuclear transfer. It is a procedure that includes inserting a skin cell nucleus into a donor egg that has been stripped of its own nucleus.
The researchers carried out this procedure on a mouse, which involved a series of complicated biological steps. As per the press release, this entire process resulted in “embryos with chromosomes contributed fromThis process starts when the skin cell nucleus experiences a significant decrease in chromosomes, triggered by cytoplasm inside the donor egg. Cytoplasm is the liquid that fills cells.
As per the release, this process is analogous to natural meiosis, in which cells split to become mature sperm or egg cells. “Researchers then fertilize the new egg with sperm, a process called in vitro fertilization. This creates a diploid embryo with two sets of chromosomes — which would ultimately result in healthy offspring with equal genetic contributions from both parents,” the authors explained in the press release.
This advancement may assist women of advanced maternal age, individuals unable to generate viable eggs as a result of prior cancer treatment, and even same-sex couples desiring genetically related offspring in the near future. 2.6-ton International Space Station junk plunging to Earth on Saturday
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