Glitazone drug use by diabetic patients associated with lower risk of primary and secondary brain cancer

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Diabetic patients who take anti-diabetic drugs - known as glitazones - long term had a lower risk of primary and secondary brain cancer compared with diabetic patients on other medications, new research led by the University of Bristol has found.

Feb 26 2024University of Bristol

Using primary care records from the UK GP database Clinical Practice Research Datalink , which contains data from a network of over 2,000 GPs from more than 670 practices across the UK, the researchers examined if this theory could be supported. The researchers found long-term glitazone drug use by diabetic patients was associated with reduced primary and secondary brain tumor risk compared with diabetic patients on other medications. No association was found between fibrate use for hyperlipidaemic patients and any type of brain tumor.

This is the largest study in diabetic patients showing a link between long-term glitazone use and decreased primary brain tumor and brain metastasis.

 

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