Reviewed by Danielle Ellis, B.Sc.Oct 30 2023 Their findings, recently published in Nature Communications, could lead to the development of new approaches targeting gut bacteria to prevent severe malaria and associated deaths.
"This plateau highlights the need for novel approaches to prevent malaria-related fatalities," said Schmidt, whose research lab is focused on investigating this global health crisis and its critical impact on children. "Presently, there are no approaches that target gut microbiota. Therefore, we believe that our approach represents an exciting opportunity."
Most of the Schmidt lab's research has been conducted using mouse models of malaria. Thanks to collaboration with several colleagues in the field, the research team was able to extend its observations by studying approximately 50 children with malaria in Uganda. They plan to continue their clinical observations by working with a cohort of over 500 children with malaria.
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