Reviewed by Lily Ramsey, LLMOct 6 2023 Researchers at Tulane University have shown for the first time that mothers are much less likely to transmit a common virus known to cause miscarriages and birth defects if they are exposed to the virus prior to becoming pregnant. The study marks a significant step toward the development of a vaccine that could protect mothers and their babies.
Researchers have long known that the risk for complications is particularly high for women infected by CMV for the first time during pregnancy, but they haven't fully understood why those who already carry the virus are less vulnerable. Researchers at the Tulane National Primate Research Center used a nonhuman primate model that closely mirrors human CMV infection and transmission. They observed that when pregnant mothers were initially infected with CMV during the first trimester, all of them transmitted the virus to their offspring, resulting in a high rate of miscarriage.
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