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Preparing for the next pandemic: Study offers improved method for tackling bird flu

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Researchers from the University of Pittsburgh and the National Institutes of Health (NIH) Vaccine Research Center have developed an improved way to test potential vaccines against bird flu. The report was published this week in the journal iScience.

that more closely mimics the typical symptoms of human infection than any such model so far. This proactive work minimizes the steps needed to quickly validate and deploy a new vaccine in a crisis.

To ensure that a future vaccine will be protective, the researchers turned to macaques, which have close anatomy and physiology to humans, making them a choice model for the testing of life-saving medicines. They first demonstrated this aerosolized infection model in research published in 2017.

 

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