Overeating and addiction may have roots in early human brain evolution and prosocial behaviors

📆 9/15/2023 7:37 PM
📰 medical_xpress

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Research led by the Department of Anthropology and School of Biomedical Sciences, Kent State University, Ohio, has investigated neuropeptide Y innervation in an area of the brain called the nucleus accumbens of various primate species, including humans. The research was focused on understanding its role in brain evolution and any implications for human health, particularly regarding addiction and eating disorders.

NPY plays a role in the reward system, emotional behavior and is associated with increased alcohol use, drug addiction and. The NAc brain region is central to motivation and action, exhibiting one of the highest densities of NPY in the brain and is of great interest to researchers investigating brain-related promoters of addiction.

Humans and chimpanzees were noted to share higher NPY in their dorsal striatum compared to gorillas and monkeys. When examining cortical NPY-ir neuron densities in Brodmann's area 22, no significant differences were found among human and nonhuman primate species.

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