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Study shows the major measure of diabetes is significantly higher in young Black patients

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LSU Health New Orleans research led by Stuart Chalew, MD, Professor of Pediatrics at LSU Health New Orleans School of Medicine, has found that HbA1c, a major metric of diabetes management, is markedly higher in black youth compared to whites at any level of mean blood glucose. The findings are published online in the Journal of Diabetes Science and Technology.

," notes Dr. Chalew."This can lead to increased occurrence of hypoglycemia in African-American patients if HbA1c is primarily used to guide insulin management of diabetes."

The research team gathered data from 118 otherwise healthy youth treated at Children's Hospital of New Orleans—33 black and 85 white patients with type 1 diabetes. Their mean age was 14.7, with an average age at diagnosis of 8.7 years, and who had diabetes for an average of 5.4 years. Fifty-one were male, and 67 were female. The researchers compared glycemic data from a factory-calibrated CGM with HbA1c taken from a venous blood draw on the day of the clinic visit.

"The combination of mean blood glucose and race accounts for a very large amount of the variation in HbA1c in the study population. These data confirm findings from many prior reports of glucose-independent racial disparity in HbA1c, which relied on a limited number of blood glucose samples for comparison."

 

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