Lupus is an autoimmune disorder characterized by autoreactive B cells and dysregulation of various immune cells, including myeloid cells. Lupus nephritis , which refers to kidney inflammation caused by lupus, is one of the most common organ manifestations associated with. The study conducted meticulous analysis on kidney biopsy samples obtained from LN patients to investigate TonEBP's involvement in these conditions.
The findings unveiled elevated expression levels of TonEBP not only within kidney cells but also infiltrating immune cells when compared to control patients. This increased expression correlated with
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