are just like M cells. Acting like gatekeepers, M cells are specialized antigen-delivery cells for the immune system in organs like the intestine and lung. They play a key role during the development of the body's immune system.
Fortuitously for the Israeli scientists, Del Castillo, under Lo's guidance, had been studying mucosal tissues—tissues that line some of the body's canals and organs—in mice in the lab and was able to answer several questions, such as where in the thymus the newly discovered cells are located and what they are doing there.
"It's still an ongoing deep puzzle that continues to attract interest," he said."The thymus offers clues to how the immune system got its start. This complicated organ, with so many different stromal cell types and interactions, is responsible for producing lymphocytes that protect us from infection."
"We found the new cells were scattered in the medullary region of the thymus," she said."This has interesting implications in terms of the role and compartmentalization of the thymus, such as how these cells may function to regulate lymphocyte training within this organ."
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