that produce insulin. To replace that insulin—the hormone that helps control blood sugar—patients must take exogenous insulin by shots or a pump and are at risk of dangerous low blood sugar events. There is no current oral treatment for this disease.
Others have found that serum IGF-1 correlates with residual beta cell function, a correlation the UAB researchers also found for the verapamil group, as measured by retention of the ability to produce endogenous insulin by the beta cells that are located in pancreatic islets.treated with or without verapamil showed that the expression of four IGF binding proteins was significantly decreased by verapamil.
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