Preclinical trials show platelets can replicate the benefits of exercise in the brain

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Preclinical trials by University of Queensland researchers have found an injection of a specific blood factor can replicate the benefits of exercise in the brain.

Dr. Odette Leiter and Dr. Tara Walker from University of Queensland's Queensland Brain Institute led a team which discovered platelets, the tiny blood cells critical for blood clotting, secrete a protein that rejuvenates neurons in aged mice in a similar way to"We know exercise increases production of new neurons in the hippocampus, the part of the brain important for learning and memory, but the mechanism hasn't been clear," Dr. Leiter said.

The researchers focused on exerkines, the biological compounds released into the bloodstream during exercise, which are believed to stimulate the exercise-induced response in the brain.

 

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