Genes that influence dopamine and adrenaline originated 650 million years ago

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Scientists decode the origins of genes required for the production, detection, and degradation of monoamines.

To fill that gap, a team of scientists at the University of Leicester in England has discovered that the genes required for these complex behaviors originated around 650 million years ago.Dr. Roberta Feuda, who led the research and was the lead author of the study, explained that there has been uncertainty around the origin of the genes required for the production, detection, and degradation of monoamines.encoded in the proteins involved in the synthesis, turnover, and detection of monoamines.

“Using the computational methods, we reconstructed the evolutionary history of these genes and show that most of the genes involved in monoamine production, modulation, and reception originated in the bilaterian stem group,” she said, in anTheir discovery suggests that the monoaminergic system evolved within the span of the end of the Cryogenian period to the beginning of the Ediacaran period, about 650−600 million years ago.

Dr. Feuda added, “This discovery will open new important research avenues that will clarify the origin of complex behaviors and if the same neurons modulate reward, addiction, aggression, feeding, and sleep.”Monoamines like serotonin, dopamine, and adrenaline/noradrenaline act as neuromodulators in the nervous system. They play a role in complex behaviors, cognitive functions such as learning and memory formation, as well as fundamental homeostatic processes such as sleep and feeding.

 

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Super-close supernova captivates record number of citizen scientistsRobert Lea is a science journalist in the U.K. whose articles have been published in Physics World, New Scientist, Astronomy Magazine, All About Space, Newsweek and ZME Science. He also writes about science communication for Elsevier and the European Journal of Physics. Rob holds a bachelor of science degree in physics and astronomy from the U.K.’s Open University. Follow him on Twitter sciencef1rst.
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