Ghana first to approve Oxford's malaria vaccine

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A keenly watched malaria vaccine from Oxford University has secured its first approval, in Ghana, as the African country ramps up efforts to combat the mosquito-borne disease that kills a child every minute.

The effort is one of several focused on addressing the disease that kills over 600,000 each year, most of them children in Africa. The complicated structure and life cycle of the malaria parasite has long stymied efforts to develop vaccines.

In contrast, GSK has committed to produce up to 15 million doses of Mosquirix every year through 2028, well under the roughly 100 million doses a year of the four-dose vaccine the WHO says is needed long-term to cover around 25 million children. Data from an ongoing phase III clinical trial in Burkina Faso, Kenya, Mali and Tanzania that has enrolled 4,800 children is expected to be published in a medical journal in the coming months.

 

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