Stanford engineers develop a new method to detect bacteria in fluids

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The new method holds the key to a faster and more affordable way to spot bacteria in liquid samples such as blood and wastewater.

A group of engineers from Stanford University developed a new laser technique that can detect and identify bacteria inThe research team used an old inkjet printer that utilizes acoustic pulses and achieved a faster, cheaper, and more accurate way to spot"We can find out not just that bacteria are present, but specifically which bacteria are in the sample – E.

Currently-used culturing methods take several hours or even days. A tuberculosis culture, for example, takes 40 days, according to Dionne. On the other hand, the new technique can be done in minutes, promising a more accurate and faster way of diagnosing infections. This could pave the way for improved antibiotic usage, safer foods, improved environmental monitoring, and faster medication development.

“Red blood cells, white blood cells, and other components in the sample are sending back their own signals, making it hard if not impossible to distinguish the microbial patterns from the noise of other cells.” The final step was to use machine learning to compare the various spectra reflecting from each printed dot of fluid to identify any bacteria in the sample.“It’s an innovative solution with the potential for life-saving impact. We are now excited for commercialization opportunities that can help redefine the standard of bacterial detection and single-cell characterization,” said senior co-author Amr Saleh, a former postdoctoral scholar in Dionne’s lab and now a professor at Cairo University.

 

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