Long-term cognitive, memory, and concentration problems that may occur in children and teenagers who have sustained traumatic brain injury may be due to reduced brain volume, researchers say., researchers from Imperial College London and Great Ormond Street Hospital investigated whether cognitive, behavioural, and emotional impairments seen after paediatric traumatic brain injury are more common in patients with abnormalities in brain volume.
It often causes long-term disability, although "outcomes are difficult to predict", they highlighted. To understand normal growth and development in different parts of the brain through childhood and adolescence, the researchers used MRI scans of more than 1200 healthy participants aged 8-22. Next, individual estimates of grey and white matter regional volume were then generated for 39 patients, average age 13.