Oxford/AstraZeneca COVID shot less effective against South African variant: study

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Feb 6: British drugmaker AstraZeneca said on Saturday its vaccine developed with the University of Oxford appeared to offer only limited protection ag...

This handout picture released by the Spanish government on February 6, 2021 shows boxes of AstraZeneca/Oxford Covid-19 vaccine after the first shipment arrived in Spain. AFP PHOTO /SPANISH GOVERNMENT HANDOUTBritish drugmaker AstraZeneca said on Saturday its vaccine developed with the University of Oxford appeared to offer only limited protection against mild disease caused by the South African variant of COVID-19, based on early data from a trial.

Among coronavirus variants currently most concerning for scientists and public health experts are the so-called British, South African and Brazilian variants, which appear to spread more swiftly than others. The company said it believed its vaccine could protect against severe disease, given that the neutralising antibody activity was equivalent to that of other COVID-19 vaccines that have demonstrated protection against severe disease.

While thousands of individual changes have arisen as the virus mutates into new variants, only a tiny minority are likely to be important or change the virus in an appreciable way, according to the British Medical Journal.

 

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