Vaccine hopes rise as Oxford jab prompts immune response among old as well as young adults

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The COVID-19 vaccine being developed by the University of Oxford and AstraZeneca Plc has been found to produce a robust immune response in elderly people.

LONDON - One of the world's leading COVID-19 experimental vaccines produces an immune response in both young and old adults, raising hopes of a path out of the gloom and economic destruction wrought by the novel coronavirus.

"It is encouraging to see immunogenicity responses were similar between older and younger adults and that reactogenicity was lower in older adults, where the COVID-19 disease severity is higher," an AstraZeneca spokesman said. The news that older people get an immune response from the vaccine is positive because the immune system weakens with age and older people are those most at risk of dying from the virus.

Asked if some people could receive a vaccine this year he told the BBC:"I don't rule that out but that is not my central expectation."Work began on the Oxford vaccine in January. Called AZD1222 or ChAdOx1 nCoV-19, the viral vector vaccine is made from a weakened version of a common cold virus that causes infections in chimpanzees.

Details of the finding are expected to be published shortly in a clinical journal, the FT said. It did not name the publication.

 

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