Genetics a poor predictor of risk for most diseases, says study | Malay Mail

New research suggests that our genes may not be as big a contributor to our risk of disease as previously thought. ― AFP pic

Carried out by scientists at University of Alberta, the new meta-analysis is the largest of its kind ever conducted, looking at two decades of data and 569 studies that explored the link between genetic variations known as single nucleotide polymorphisms and different diseases and health conditions.

“Simply put, DNA is not your destiny, and SNPs are duds for disease prediction,” said co-author David Wishart. “The vast majority of diseases ― including many cancers, diabetes and Alzheimer's disease ― have a genetic contribution of five to 10 per cent at best.” “Despite these rare exceptions, it is becoming increasingly clear that the risks for getting most diseases arise from your metabolism, your environment, your lifestyle or your exposure to various kinds of nutrients, chemicals, bacteria or viruses,” explained Wishart.

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